Sierocytární receptor jądrowy RORgammat kieruje program różnicowania

Sierocytární receptor jądrowy RORgammat kieruje program różnicowania prozapalnych komór pomocných IL-17 + T.

 Nedávno bylo prokázáno, že T- lymfocyty produkující IL-17  obsahují odlišnou linii prozánětlivých pomocných T  buněk , nazývaných Th17  buňky , které jsou hlavními přispěvateli ok autoimunitnímu onemocnění. Ukazujeme zde, že osiřelý jaderný receptor RORgammat je klíčovým transkripčním faktorem, který řídí diferenciaci této efektorové  buněčné  linie.

RORgammat indukuje transkripci genů kódujících IL-17 a související cytokin IL-17F v naivních CD4 (+) T pomocných  buňkách  a je nezbytný professional jejich expresi v reakci na IL-6 a TGF-beta, což je známo, že cytokiny indukují IL- 17.

Buňky Th17   jsou konstitutivně přítomné v intestinální lamina propria, exprimují RORgammat a chybí u myší s deficitem RORgammat nebo IL-6. Myši s RORgammat-deficientními T buňkami oslabily   autoimunitní onemocnění a postrádají tkáňově infiltrující Th17  buňky . Společně tyto studie naznačují, že RORgammat je klíčovým regulátorem imunitní homeostázy a zdůrazňuje jeho potenciál jako terapeutického cíle při zánětlivých onemocněních.

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RapidSeq High Yield Directional mRNA Sample Prep Kit - With Aligner 25-36

KS073012-III 1 Kit
EUR 1142
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

RapidSeq High Yield Small RNA Sample Prep Kit - With Aligner 25-36

KS074012-III 1 Kit
EUR 1021
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Attoglow Western Blot Analysis Kit- with Millennium Enhancer, Anti chicken secondary antibody

K3171120-III 1200 cm2
EUR 246
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Attoglow Western Blot Analysis Kit- with Millennium Enhancer, Anti chicken secondary antibody

K3171250-III 2500 cm2
EUR 310
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Mounting Medium

4300 3 ml
EUR 180.5
Description: This is Mounting medium (non-fading) used for maintaining optimal conditions needed to obtain the maximum fluorescence emission from Fluorescein.

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450 500 ml
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451 500 ml
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EverBrite Mounting Medium

23001 10mL
EUR 178
Description: Minimum order quantity: 1 unit of 10mL

Recovery Medium - 6x12mL

1711 4/PK
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SuperMOUNT? Mounting Medium

1211-20
EUR 201

Aqueous Mounting Medium

AR1018 10mL X5 (Enough for 800-1200 assays)
EUR 80

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AR1109 10mL (for 1000 assays)
EUR 65

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E05-108-10kg 10 kg
EUR 858

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abx098879-500ml 500 ml
EUR 175
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CM034-050 500ml
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CM034-300 6x500ml
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CM034-310 10x500ml
EUR 219

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CM034-320 20x500ml
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EUR 585

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CM063-050 500ml
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CM063-300 6x500ml
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CM063-310 10x500ml
EUR 313

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CM063-320 20x500ml
EUR 604

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CM063-350 50x500ml
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AddexBio Cryopreservation Medium

C0002-20mL RT vial
EUR 104

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C03-131-10kg 10 kg
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C03-131-2Kg 2 Kg
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CP003-005 5L
EUR 113

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CP003-010 10X1L
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CP017-010 10X1L
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CP017-500 50L
EUR 126

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CP037-010 10X1L
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EUR 96

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EUR 530

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SD50M-100 100 g
EUR 344

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SD50M-500 500 g
EUR 1285

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SGM001 500 ml
EUR 244

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T20-114-10kg 10 kg
EUR 675

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T20-114-2kg 2kg
EUR 186

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T20-114-500g 500 g
EUR 87

THIOGLYCOLLATE MEDIUM, BREWER

T20-118-10kg 10 kg
EUR 1364

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T20-118-500g 500 g
EUR 128

2XYT MICROBIAL MEDIUM

X24-102-10kg 10 kg
EUR 614

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X24-102-2Kg 2 Kg
EUR 173

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EUR 83

H Medium Broth

DJ1019 100g
EUR 60.88
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Angiotensin III (Ang III) Antibody

20-abx101595
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
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Bovine Antithrombin III (AT III) Antibody

22111-05011 150 ug
EUR 217

Angiotensin III (Ang III) Protein (OVA)

20-abx651227
  • EUR 258.00
  • EUR 189.00
  • EUR 578.00
  • EUR 286.00
  • EUR 230.00
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Filipin III

2744-1000
EUR 294

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2744-500
EUR 196

Leucokinin III

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5-00640 4 x 5mg Ask for price

Jingzhaotoxin III

B5763-.1 100 ug
EUR 601

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B6034-.5 500 µg
EUR 173

Płynny mannequin mozaiki struktury błon komórkowych.

 Je představen mannequin tekuté mozaiky professional hrubou organizaci a strukturu proteinů a lipidů biologických membrán. Mannequin je v souladu s omezeními uloženými termodynamikou. V tomto modelu jsou proteiny, které jsou nedílnou součástí membrány, heterogenní sada globulárních molekul, každá uspořádaná do amfipatické struktury, tj.

S iontovými a vysoce polárními skupinami vyčnívajícími z membrány do vodné fáze, a nepolárními skupinami z velké části pohřben v hydrofobním vnitřku membrány. Tyto globulární molekuly jsou částečně zabudovány do matice fosfolipidů. Převážná část fosfolipidu je organizována jako diskontinuální tekutá dvojvrstva, i když malá část lipidu může specificky interagovat s membránovými proteiny.

Struktura tekuté mozaiky je tedy formálně analogická s dvourozměrně orientovaným roztokem integrálních proteinů (nebo lipoproteinů) ve viskózním fosfolipidovém dvojvrstvém rozpouštědle. Jsou popsány nedávné experimenty s nejrůznějšími technikami a několika různými membránovými systémy, které jsou v souladu s modelem fluidní mozaiky a přidávají ok němu mnoho podrobností. 

Zdá se proto vhodné navrhnout možné mechanismy professional různé membránové funkce a membránou zprostředkované jevy ve světle modelu. Jako příklady jsou navrženy experimentálně testovatelné mechanismy professional   změny buněčného povrchu v maligní transformaci a professional kooperativní účinky projevené v interakcích membrán s některými specifickými ligandy.

Doklad přidaný jako důkaz: Od doby, kdy byl tento článek napsán, jsme získali elektronový mikroskopický důkaz (69), že vazebná místa konkanavalinu A na membránách myších fibroblastů transformovaných virem

SV40 ( buňky 3T3  ) jsou více shlukována než místa na membránách normální  buňky , jak předpovídá hypotéza představená na obr. 7B. T-here se také objevila studie Taylor et al. (70) ukazující pozoruhodné účinky produkované na  lymfocyty  přidáním protilátek namířených proti jejich povrchovým imunoglobulinovým molekulám.

Protilátky indukují redistribuci a pinocytózu těchto povrchových imunoglobulinů, takže během asi 30 minut při teplotě 37 ° C jsou povrchové imunoglobuliny zcela smeteny z membrány. Okay těmto účinkům však nedochází, pokud jsou bivalentní protilátky nahrazeny jejich univalentními fragmenty Fab nebo pokud jsou experimenty s protilátkami prováděny při 0 ° C místo 37 ° C.

  • Tyto a související výsledky silně naznačují, že bivalentní protilátky produkují agregaci povrchových molekul imunoglobulinu v rovině membrány, ke kterému může dojít pouze v případě, že molekuly imunoglobulinu mohou v membráně volně difundovat . 
  • Tato agregace pakZdá se, že spouští pinocytózu membránových složek nějakým neznámým mechanismem.
  • Takové membránové transformace mohou mít zásadní význam při indukci protilátkové odpovědi na antigen, stejně jako při jiných procesech  buněčné  diferenciace.

Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika sprzyja przywilejowi imunologicznemu i pozwala przewidzieć skrócenie czasu przeżycia

Regulační T (T (reg))  buňky  zprostředkovávají homeostatickou periferní toleranci potlačením autoreaktivních T  buněk . Selhání protinádorové imunity hostitele může být způsobeno přehnanou supresí s nádorem asociovaných antigen reaktivních  lymfocytů  zprostředkovaných T (reg)  buňkami ; chybí však definitivní důkazy o tom, že T (reg)  buňky  mají imunopatologickou roli v lidské rakovině.

 

Zde ukážeme v podrobných studiích CD4 (+) CD25 (+) FOXP3 (+) T (reg)  buněk  u 104 jedinců postižených karcinomem vaječníků, že T (reg) buňky lidského nádoru   potlačují  imunitu T- buněk specifickou professional nádor  a přispívají ok růstu lidských nádorů in vivo.

Ukazujeme také, že nádorové T (reg)  buňky  jsou spojeny s vysokým rizikem úmrtí a sníženým přežitím. Lidské T (reg)  buňky se  přednostně pohybují a akumulují v nádorech a ascitu, ale zřídka vstupují do odtokových lymfatických uzlin v pozdějších stadiích rakoviny.

Nádorové  buňky  a mikroprostředí makrofágy produkují chemokin CCL22, který zprostředkovává přenos T (reg)  buněk  do nádoru. Tento specifický nábor T (reg)  buněk  představuje mechanismus, kterým mohou nádory podporovat imunitní privilegia. Blokování  migrace nebo funkce T (reg)  buněk tedy může pomoci porazit lidskou rakovinu.

Przywracanie funkcji wyczerpanych limfocytów T CD8 podczas przewlekłej infekcji wirusowej.

Funkční poškození antigen-specifických T  buněk  je určující charakteristikou mnoha chronických infekcí, ale základní mechanismy  dysfunkce T- buněk nejsou dobře známy. Abychom se touto otázkou  zabývali , analyzovali jsme geny exprimované ve funkčně poškozených virově specifických CD8 T  buňkách přítomných u myší chronicky infikovaných virem lymfocytární choriomeningitidy (LCMV) a porovnali jsme je s genovým profilem CD8 T buněk s funkční pamětí  .

Zde hlásíme, že PD-1 (programovaná smrt 1; také známá jako Pdcd1) byla selektivně upregulována vyčerpanými T  buňkamia že in vivo podávání protilátek, které blokovaly interakci tohoto inhibičního receptoru s jeho ligandem, PD-L1 (také známý jako B7-H1), zesílilo  reakce T- buněk .

Zejména jsme zjistili, že i u trvale infikovaných myší, kterým chyběla  pomoc CD4 T- buněk , měla blokáda inhibiční dráhy PD-1 / PD-L1 příznivý účinek na „bezmocné“ CD8 T  buňky a obnovila jejich schopnost podstoupit proliferaci , vylučují cytokiny, zabíjejí infikované

buňky  a snižují virovou zátěž. Blokáda inhibiční dráhy CTLA-4 (cytotoxický T- lymfocyt spojený s proteinem 4) neměla žádný účinek na  funkci T- buněk ani na virovou kontrolu. Tyto studie identifikují specifický mechanismus  vyčerpání T- buněk a definují potenciálně účinnou imunologickou strategii professional léčbu chronických virových infekcí.

 

Bead Sample Pack - 50mL Set

BSP-50B2 1pack
EUR 404
Description: Bead sample pack for Bullet Blender 50mL tube models. Includes 20mL of: ZROB05, ZROB20, SSB02, SSB14B, SSB48, SSB60, SSUFO35 and SSUFO56.

Bead Sample Pack - 5E Set

BSP-5E 1pack
EUR 252
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Bead Sample Pack - 5M Set

BSP-5Y 1pack
EUR 241
Description: Bead sample pack for Bullet Blender 5mL Storm models. Includes 10mL of: ZROB015, ZROB05, ZROB20, SSB02, SSB14B, SSB32, SSB60, SSB110 and SSUFO35.

Bead Sample Pack - Full Set

BSP-ALL2 1pack
EUR 384
Description: Bead sample pack inlcudes sampling of all 20 bead types in 10mL tubes.

Bead Sample Pack - Microcentrifuge Set

BSP-MC2 1pack
EUR 232
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Bead Sample Pack - Organ Tissues

BSP-OT3 1pack
EUR 235
Description: Bead sample pack for homogenization of organ tissues. Includes 10mL of: ZROB05, ZROB10, ZROB20, SSB14B, SSB32 and SSUFO35.

All Sample Diluents Sample Pack

KF17355 3X100 ml
EUR 272

Red Blood Cell Sample Pack

88R-1050 6 x 2 ml
EUR 403
Description: Horse, Mouse, Rabbit, Sheep, Bovine and Chicken glutaraldehyde stabilized blood cell samples

Exosome isolation Solution - Cell Media/ Urine (easy version of P100, 95% pure exosome) sample

P100EZ-sample NULL
EUR 0

TMB Peroxidase Substrate SAMPLE PACK

42R-TB101 3 x 100 ml
EUR 300
Description: 100mL of 3 different TMB Peroxidase Substrates ready to use in immunoassays: Ultra sensitivite, Highly Sensitive, and Slow Acting.

3 Blocking Buffer Sample Pack

KF17340 3 x 100 ml
EUR 205

All Assay Diluents Sample Pack

KF17351 4X100 ml
EUR 272

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome) sample

P101EZ--sample NULL
EUR 0

Water, 0.1um Filtered, cell cultures tested

W0900-050 500 ml
EUR 68

Water, 0.1um Filtered, cell cultures tested

W0900-310 10x500 ml
EUR 169

Water, 0.1um Filtered, cell cultures tested

W0900-350 50x500 ml
EUR 523

Micro Bead Sterlizer

B1201-E 1 PC
EUR 542.7
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Micro Bead Sterlizer

B1202-E 1 PC
EUR 84.14
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Refill Glass Beads

B1201-BEAD 1 PC
EUR 117.78
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Column Packing Kit

PACK-KIT 1pack
EUR 1035
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Sample Diluent

I094 1000 ml
EUR 519
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Description: Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Sample Diluent

I094-100 100 ml
EUR 211
  • Product category: Buffer solution
Description: Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Sample Diluent

I094-500 500 ml
EUR 373
  • Product category: Buffer solution
Description: Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Bangs Lab Bead Solution

SOLN1-1000 1000 ML
EUR 155.06
Description: Bangs Lab Bead Solution is ready-to-use solution and is suitable for dilution and/or storage of plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Solution

SOLN1-2000 2000 ML
EUR 212.7
Description: Bangs Lab Bead Solution is ready-to-use solution and is suitable for dilution and/or storage of plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Solution

SOLN1-500 500 ML
EUR 98.51
Description: Bangs Lab Bead Solution is ready-to-use solution and is suitable for dilution and/or storage of plain, dyed, or functionalized polymer microspheres

Adapter pack

C1005-AC2 1 PC
EUR 98.5
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Adapter pack

C3100-ADP 1 PC
EUR 164.18
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EZ Pack

A2501 1 PC
EUR 365.66
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EZ Pack

A2505 1 PC
EUR 183.03
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Long-term Cell Tracer 580 (Green) sample

P710GS NULL
EUR 0

Long-term Cell Tracer 580 (Yellow) sample

P710YS NULL
EUR 0

Sample diluent buffer

AR1106-1 30ml
EUR 91

Rotavirus Positive Sample

DAG-H10377 1 ml dry ice
EUR 1105

RSV Positive Sample

DAG-H10378 1 ml dry ice
EUR 1105

DNA Sample Diluent

D006-100 100 ml
EUR 373
  • Product category: Buffer solution
Description: DNA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

DNA Sample Diluent

D006-1000 1000 ml
EUR 1167
  • Product category: Buffer solution
Description: DNA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

DNA Sample Diluent

D006-500 500 ml
EUR 726
  • Product category: Buffer solution
Description: DNA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Sample Diluent Buffer

abx296001-20ml 20 ml
EUR 91
  • Shipped within 5-10 working days.

BSA Sample Diluent

F031A 1000 ml
EUR 488
  • Product category: Buffer solution
Description: BSA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

BSA Sample Diluent

F031A-100 100 ml
EUR 195
  • Product category: Buffer solution
Description: BSA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

BSA Sample Diluent

F031A-500 500 ml
EUR 411
  • Product category: Buffer solution
Description: BSA Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Sample Denaturing Buffer

F054 12 ml
EUR 195
  • Product category: Buffer solution
Description: Sample Denaturing Buffer by Cygnus Technologies is available in Europe via Gentaur.

Sample Treatment Buffer

F175 1000 ml
EUR 411
  • Product category: Buffer solution
Description: Sample Treatment Buffer by Cygnus Technologies is available in Europe via Gentaur.

Sample Treatment Buffer

F175-100 100 ml
EUR 219
  • Product category: Buffer solution
Description: Sample Treatment Buffer by Cygnus Technologies is available in Europe via Gentaur.

Sample Treatment Plate

F402 1x 96 wells plate
EUR 103
  • Product category: Microplates
Description: Sample Treatment Plate by Cygnus Technologies is available in Europe via Gentaur.

ELISA Sample Diluent

ESD125 125 ml
EUR 80

ELISA Sample Diluent

ESD500 500 ml
EUR 109

ELISA Sample Diluent

ESD999 1000 ml
EUR 157

Sample Diluent Buffer

I028-100 100 ml
EUR 211
  • Product category: Buffer solution
Description: Sample Diluent Buffer by Cygnus Technologies is available in Europe via Gentaur.

Sample Diluent Buffer

I028-1000 1000 ml
EUR 519
  • Product category: Buffer solution
Description: Sample Diluent Buffer by Cygnus Technologies is available in Europe via Gentaur.

Sample Diluent Buffer

I028-500 500 ml
EUR 373
  • Product category: Buffer solution
Description: Sample Diluent Buffer by Cygnus Technologies is available in Europe via Gentaur.

HEPES Sample Diluent

I050 1000 ml
EUR 527
  • Product category: Buffer solution
Description: HEPES Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

HEPES Sample Diluent

I050-100 100 ml
EUR 219
  • Product category: Buffer solution
Description: HEPES Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

HEPES Sample Diluent

I050-500 500 ml
EUR 334
  • Product category: Buffer solution
Description: HEPES Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Sample Diluent, 60ML

X028-60ML 60ML
EUR 143

Protein A Tell-Tale Gold Ribbon Sample Pack, 3 x (1 cm x 30 cm)

TTGA-SP3-B090 3 x (1 cm x 30 cm)
EUR 227.67
  • Product Category: Gold Ribbon
Description: The pack contains polyester ribbon, which is soaked with 0.13 O.D./cm2 concentration with Protein G conjugated to gold nanoparticles.

Protein G Tell-Tale Gold Ribbon Sample Pack, 3 x (1 cm x 30 cm)

TTGG-SP3-B090 3 x (1 cm x 30 cm)
EUR 227.67
  • Product Category: Gold Ribbon
Description: The pack contains polyester ribbon, which is soaked with 3 different concentrations with Protein G conjugated to gold nanoparticles.

DEAE Rapid Run Agarose Bead

DEAERR-25 25 ml
EUR 102

DEAE Rapid Run Agarose Bead

DEAERR-300 300 ml
EUR 492

CM Rapid Run Agarose Bead

CMRR-25 25 ml
EUR 102

CM Rapid Run Agarose Bead

CMRR-300 300 ml
EUR 492

SP Rapid Run Agarose Bead

SPRR-25 25 ml
EUR 102

SP Rapid Run Agarose Bead

SPRR-300 300 ml
EUR 492

Protein A/G Tell-Tale Gold Ribbon Sample Pack, 3 x (1 cm x 30 cm)

TTGAG-SP3-B090 3 x (1 cm x 30 cm)
EUR 227.67
  • Product Category: Gold Ribbon
Description: The pack contains polyester ribbon, which is soaked with 3 different concentrations with Protein A and G conjugated to gold nanoparticles.

Replacement generator pack

D1000-M5 1 PC
EUR 531.32
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Replacement generator pack

D1000-M7 1 PC
EUR 415.61
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

0.2ml Adapter pack

C1008-A2-6 1 PC
EUR 84.94
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

0.2ml Adapter pack

C1008-A2-9 1 PC
EUR 395.96
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

0.5ml Adapter pack

C1008-A5-6 1 PC
EUR 80.95
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

0.5ml Adapter pack

C1008-A5-8 1 PC
EUR 84.94
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

mini cooling pack

EVS1100-COOL ea
EUR 48

maxi cooling pack

EVS1300-COOL ea
EUR 82

Safe-Pack™

G108-P G108-WGR
EUR 104

Spatulas (Large Pack)

SPAT1 50pack
EUR 301
Description: Individually wrapped spatulas. RNase/DNase free, non-pyrogenic, antistatic, sterile, plastic. Pack of 50.

Spatulas (Small Pack)

SPAT2 10pack
EUR 133
Description: Individually wrapped spatulas. RNase/DNase free, non-pyrogenic, antistatic, sterile, plastic. Pack of 10.

CometAssay HT Sample Kit

4252-040-K 40 Tests
EUR 428

Deproteinizing Sample Preparation Kit

55R-1542 200 assays
EUR 450
Description: Deproteinizing Sample Preparation Kit for use in the research laboratory

Salivary Sample Collection Kit

55R-IB76305 500 tests
EUR 301
Description: Salivary sample collection kit for the detection of free Salivary proteins and enzymes in the research laboratory

comb 10 sample, 0.8mm

EVS3100-C10-0.8 ea
EUR 59

comb 10 sample, 1.5mm

EVS3100-C10-1.5 ea
EUR 59

comb 12 sample, 0.8mm

EVS3100-C12-0.8 ea
EUR 59

comb 12 sample, 1.5mm

EVS3100-C12-1.5 ea
EUR 59

comb 6 sample, 0.8mm

EVS3100-C6-0.8 ea
EUR 59

comb 6 sample, 1.5mm

EVS3100-C6-1.5 ea
EUR 59

comb 8 sample, 0.8mm

EVS3100-C8-0.8 ea
EUR 59

comb 8 sample, 1.5mm

EVS3100-C8-1.5 ea
EUR 59

comb 10 sample, 0.8mm

EVS3200-C10-0.8 ea
EUR 65

comb 10 sample, 1.5mm

EVS3200-C10-1.5 ea
EUR 65

comb 15 sample, 0.8mm

EVS3200-C15-0.8 ea
EUR 65

comb 15 sample, 1.5mm

EVS3200-C15-1.5 ea
EUR 65

comb 20 sample, 0.8mm

EVS3200-C20-0.8 ea
EUR 65

comb 20 sample, 1.5mm

EVS3200-C20-1.5 ea
EUR 65

comb 25 sample, 0.8mm

EVS3200-C25-0.8 ea
EUR 65

comb 25 sample, 1.5mm

EVS3200-C25-1.5 ea
EUR 65

comb 10 sample, 0.8mm

EVS3300-C10-0.8 ea
EUR 65

comb 10 sample, 1.5mm

EVS3300-C10-1.5 ea
EUR 65

comb 15 sample, 0.8mm

EVS3300-C15-0.8 ea
EUR 65

comb 15 sample, 1.5mm

EVS3300-C15-1.5 ea
EUR 65

comb 20 sample, 0.8mm

EVS3300-C20-0.8 ea
EUR 65

comb 20 sample, 1.5mm

EVS3300-C20-1.5 ea
EUR 65

comb 25 sample, 0.8mm

EVS3300-C25-0.8 ea
EUR 65

comb 25 sample, 1.5mm

EVS3300-C25-1.5 ea
EUR 65

SP2/0 Sample Diluent

F183A 1000 ml
EUR 835
  • Product category: Buffer solution
Description: SP2/0 Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

SP2/0 Sample Diluent

F183A-100 100 ml
EUR 257
  • Product category: Buffer solution
Description: SP2/0 Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

SP2/0 Sample Diluent

F183A-500 500 ml
EUR 488
  • Product category: Buffer solution
Description: SP2/0 Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Goat IgG Sample Diluent

F213A 1000 ml
EUR 565
  • Product category: Buffer solution
Description: Goat IgG Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Goat IgG Sample Diluent

F213A-100 100 ml
EUR 257
  • Product category: Buffer solution
Description: Goat IgG Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Goat IgG Sample Diluent

F213A-500 500 ml
EUR 411
  • Product category: Buffer solution
Description: Goat IgG Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

NS/0 Sample Diluent

F223A 1000 ml
EUR 835
  • Product category: Buffer solution
Description: NS/0 Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

NS/0 Sample Diluent

F223A-100 100 ml
EUR 257
  • Product category: Buffer solution
Description: NS/0 Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

NS/0 Sample Diluent

F223A-500 500 ml
EUR 488
  • Product category: Buffer solution
Description: NS/0 Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

A549 Sample Diluent, 100mL

F233A-100 100 ml
EUR 257
  • Product category: Buffer solution
Description: A549 Sample Diluent, 100mL by Cygnus Technologies is available in Europe via Gentaur.

A549 Sample Diluent, 500mL

F233A-500 500 ml
EUR 411
  • Product category: Buffer solution
Description: A549 Sample Diluent, 500mL by Cygnus Technologies is available in Europe via Gentaur.

Neptune Sample Diluent-SD3

KF17354 500 ml
EUR 244

Deproteinizing Sample Preparation Kit

K808-200
EUR 338

Deproteinizing Sample Preparation Kit

K2184-200 200 assays
EUR 321

ProtoGel Sample Prep Kit

NAT1248 EACH
EUR 186

RoomTemp Sample Lysis Kit

P073-01 250 rxn (5 ml)
EUR 212

RoomTemp Sample Lysis Kit

P073-02 1000 rxn ( 20 ml)
EUR 473

RoomTemp Sample Lysis Kit

P073-03 5000 rxn (100 ml)
EUR 1400

Inactivated ADV Positive Sample

VAng-Lsx0001-inquire inquire Ask for price
Description: ADV Positive Sample, natural antigen.

Hemoglobin Sample Diluent, 50ML

X052-50ML 50ML
EUR 153

Sample Diluent (Conc.), 12ML

X074-12ML 12ML
EUR 123

Sample Diluent (Conc.), 60ML

X074-60ML 60ML
EUR 143

Recombinant RSV Positive Sample

VAng-Lsx0452-inquire inquire Ask for price
Description: RSV Positive Sample.

Coronavirus Sample Preparation Solution

M1461-50 50 ml Ask for price

Anti-DDK(FLAG) Agarose bead Conjugated

D4501-001 1ml
EUR 550

Anti-DDK(FLAG) Agarose bead Conjugated

D4501-005 5ml
EUR 1373

Nickel NTA Magnetic Agarose Bead (5%)

MagNTANi5-10 10ml suspension
EUR 284

Nickel NTA Magnetic Agarose Bead (5%)

MagNTANi5-2 2ml suspension
EUR 99

Nickel NTA Magnetic Agarose Bead (5%)

MagNTANi5-5 5ml suspension
EUR 174

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric

CBA-135 96 assays
EUR 821
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric

CBA-135-5 5 x 96 assays
EUR 3356
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

CBA-140 96 assays
EUR 856
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

CBA-140-5 5 x 96 assays
EUR 3483
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

293AD Cell Line

AD-100 1 vial
EUR 461
Description: The 293AD Cell Line is derived from the parental 293 cells but selected for attributes that increase adenovirus production, including firmer attachment and larger surface area.

293AAV Cell Line

AAV-100 1 vial
EUR 508
Description: The 293AAV Cell Line is derived from the parental 293 cells but selected for attributes that increase AAV production, including firmer attachment and larger surface area.

293LTV Cell Line

LTV-100 1 vial
EUR 508
Description: The 293LTV Cell Line is derived from the parental 293 cells but selected for attributes that increase lentiviral production, including fimrer attachment and larger surface area.

293RTV Cell Line

RV-100 1 vial
EUR 508
Description: The 293RTV Cell Line is derived from the parental 293 cells but selected for attributes that increase retroviral production, including fimrer attachment and larger surface area.

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)

CBA-325 96 assays
EUR 856
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)

CBA-325-5 5 x 96 assays
EUR 3361
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

ELISA Starter Pack Kit

55R-E101PK 1 kit
EUR 563
Description: ELISA reagent tool kit for use as a starter pack for researchers

TBS Blocking Buffer Pack

AR0143 200mL/pack
EUR 65

TBS Wash Buffer Pack

AR0144 500mL/pack
EUR 60

PBS Wash Buffer Pack

AR1155 500mL/pack
EUR 65

cool-pack and platfom

EHS1100-COOL ea
EUR 90

cool-pack and platfom

EHS1200-COOL ea
EUR 107

cool-pack and platfom

EHS1300-COOL ea
EUR 124

cool-pack and platfom

EHS1400-COOL ea
EUR 124

cool-pack and platfom

EHS1500-COOL ea
EUR 149

Measuring Spoon (Large Pack)

SPN1 200pack
EUR 479
Description: Individually wrapped 1.2mL spoons. Sterile. Pack of 200.

Measuring Spoon (Small Pack)

SPN2 20pack
EUR 130
Description: Individually wrapped 1.2mL spoons. Sterile. Pack of 20.

MDR Sampler Pack antibody

STJ16100969 1 pack
EUR 666

TruStrip Sample Transfer Strips, 5-ul, 50/Pk (without sample tracking dye)

STS-05-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 100-ul, 50/Pk (without sample tracking dye)

STS-100-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 15-ul, 50/Pk (without sample tracking dye)

STS-15-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 200-ul, 50/Pk (without sample tracking dye)

STS-200-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 25-ul, 50/Pk (without sample tracking dye)

STS-25-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 400-ul, 50/Pk (without sample tracking dye)

STS-400-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 50-ul, 50/Pk (without sample tracking dye)

STS-50-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 800-ul, 50/Pk (without sample tracking dye)

STS-800-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 5-ul, 50/Pk (with sample tracking dye)

STSD-05-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 100-ul, 50/Pk (with sample tracking dye)

STSD-100-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 15-ul, 50/Pk (with sample tracking dye)

STSD-15-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 200-ul, 50/Pk (with sample tracking dye)

STSD-200-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 25-ul, 50/Pk (with sample tracking dye)

STSD-25-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 400-ul, 50/Pk (with sample tracking dye)

STSD-400-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 50-ul, 50/Pk (with sample tracking dye)

STSD-50-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 800-ul, 50/Pk (with sample tracking dye)

STSD-800-50 1 Pk Ask for price

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size

CBA-135-T 24 assays
EUR 432
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

293/GFP Cell Line

AKR-200 1 vial
EUR 572
Description: 293/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

T47D/GFP Cell Line

AKR-208 1 vial
EUR 572
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

A549/GFP Cell Line

AKR-209 1 vial
EUR 572
Description: A549/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

HeLa/GFP Cell Line

AKR-213 1 vial
EUR 572
Description: HeLa/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

NIH3T3/GFP Cell Line

AKR-214 1 vial
EUR 572
Description: NIH3T3/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

NIH3T3/Cas9 Cell Line

AKR-5104 1 vial
EUR 572

293/Cas9 Cell Line

AKR-5110 1 vial
EUR 572

HeLa/Cas9 Cell Line

AKR-5111 1 vial
EUR 572

Protonex™ Red 600-Latex Bead Conjugate

21209 1 mL
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Bangs Lab Bead Coupling Buffer, pH 4.5

BUFF1-1000 1000 ML
EUR 155.06
Description: Bangs Lab Bead Coupling Buffer, pH 4.5 is ready-to-use buffer and is suitable for coupling or wash buffers for plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Coupling Buffer, pH 4.5

BUFF1-2000 2000 ML
EUR 212.7
Description: Bangs Lab Bead Coupling Buffer, pH 4.5 is ready-to-use buffer and is suitable for coupling or wash buffers for plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Coupling Buffer, pH 4.5

BUFF1-250 250 ML
EUR 87.64
Description: Bangs Lab Bead Coupling Buffer, pH 4.5 is ready-to-use buffer and is suitable for coupling or wash buffers for plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Coupling Buffer, pH 4.5

BUFF1-500 500 ML
EUR 120.26
Description: Bangs Lab Bead Coupling Buffer, pH 4.5 is ready-to-use buffer and is suitable for coupling or wash buffers for plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Coupling Buffer, pH 6.0

BUFF2-1000 1000 ML
EUR 155.06
Description: Bangs Lab Bead Coupling Buffer, pH 6.0 is ready-to-use buffer and is suitable for coupling or wash buffers for plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Coupling Buffer, pH 6.0

BUFF2-2000 2000 ML
EUR 212.7
Description: Bangs Lab Bead Coupling Buffer, pH 6.0 is ready-to-use buffer and is suitable for coupling or wash buffers for plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Coupling Buffer, pH 6.0

BUFF2-250 250 ML
EUR 87.64
Description: Bangs Lab Bead Coupling Buffer, pH 6.0 is ready-to-use buffer and is suitable for coupling or wash buffers for plain, dyed, or functionalized polymer microspheres

Bangs Lab Bead Coupling Buffer, pH 6.0

BUFF2-500 500 ML
EUR 120.26
Description: Bangs Lab Bead Coupling Buffer, pH 6.0 is ready-to-use buffer and is suitable for coupling or wash buffers for plain, dyed, or functionalized polymer microspheres

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